Culture of Mycobacterium smegmatis in Different Carbon Sources to Induce In Vitro Cholesterol Consumption Leads to Alterations in the Host Cells after Infection: A Macrophage Proteomics Analysis
During tuberculosis, Mycobacterium uses host macrophage cholesterol as a carbon and energy source.To mimic these conditions, Mycobacterium smegmatis can be cultured in minimal medium (MM) to induce cholesterol consumption in vitro.During cultivation, M.smegmatis consumes NORMAL/OILY HAIR CONDITIONER MM cholesterol and changes the accumulation of ce